The Healthcare Technology Report is pleased to announce The Top 25 Healthcare Software Companies of 2025. Abridge set the pace with one of the largest healthcare AI funding rounds of the year, raising $300 million to expand its generative AI platform, with adoption spreading rapidly across leading health systems. Epic Systems followed with the launch of Comet, a predictive intelligence system built on its Cosmos dataset of more than 100 billion medical events, promising to reshape risk prediction and clinical decision-making across hundreds of millions of patient records worldwide.
Industry consolidation and strategic partnerships have also defined the year. Kyruus Health, already on track to surpass $150 million in annual recurring revenue, agreed to be acquired by RevSpring in a move that unifies search, access, intake, and payments into a single consumer experience. Meanwhile, Komodo Health launched Marmot, a healthcare-native AI engine delivering verifiable analytics in minutes, while also joining with Nasdaq to introduce a first-of-its-kind medical claims dataset for financial institutions.
The achievements span well beyond these landmark moves. This year’s awardees have helped define the future of healthcare delivery through scale, advanced analytics, and AI-driven solutions that improve access, efficiency, and outcomes. Please join us in recognizing The Top 25 Healthcare Software Companies of 2025.
Abridge builds healthcare-native generative AI that transforms clinician–patient conversations into structured notes in real time, with Epic integration across Haiku, Hyperspace, and ASAP. Its platform is deployed across more than 150 health systems, supporting 55 specialties in 28 languages, and is being adopted enterprise-wide by organizations such as Kaiser Permanente and Johns Hopkins Medicine.
In June 2025, Abridge raised $300 million in a Series E led by Andreessen Horowitz and Khosla Ventures, bringing total funding to approximately $800 million. That same year, the company launched Abridge Inside for Emergency Medicine, expanded into inpatient documentation and orders workflows, and announced collaborations with Wolters Kluwer UpToDate, Epic, and Mayo Clinic to extend ambient documentation to nurses. Abridge expects to support over 50 million medical conversations this year, reducing clerical workload for providers.
Chief Executive Officer and Co-Founder Shiv Rao, MD, a practicing cardiologist, has led Abridge since inception, guiding its growth from a startup into one of the healthcare industry’s most widely adopted AI platforms.
Founded over 25 years ago, Qualifacts is one of the largest providers of behavioral health and human services EHR platforms in the U.S., serving more than 2,700 organizations nationwide, including one-third of Certified Community Behavioral Health Centers. Owned by private equity firm Warburg Pincus, the company delivers its cloud-based solutions—Credible, CareLogic, and InSync—to streamline clinical workflows, billing, and compliance for providers from small practices to multi-state enterprises.
In September 2025, Qualifacts became the first EHR solutions provider to achieve ISO 42001:2023 certification for AI Management Systems, highlighting its commitment to secure, transparent, and responsible AI. Earlier in the year, the company expanded its Qualifacts iQ suite with iQ Assistant, a free in-workflow AI tool now adopted by hundreds of organizations to simplify documentation and onboarding. Chief Executive Officer Josh Schoeller, who joined in 2023, has overseen the company’s AI initiatives while maintaining a focus on provider efficiency and patient outcomes.
PartsSource is a B2B marketplace and supply chain software platform for the healthcare industry, connecting more than 5,000 hospitals, 15,000 clinical sites, and 6,000 OEMs and suppliers with instant access to over four million mission-critical products and services. The platform helps providers reduce costs, minimize downtime, and improve asset reliability across the healthcare ecosystem.
In June 2025, the company announced further development of Asset Uptime, the first multi-vendor, multi-modality Asset Health Record co-developed with major health systems to optimize utilization and reduce unplanned downtime. This followed the company’s acquisitions of Glassbeam, a leader in medical equipment analytics, and NVRT Labs, a developer of virtual reality training. Philip Settimi has led the company as President and Chief Executive Officer since 2014, with Bain Capital Private Equity as majority investor since 2021.
Komodo Health provides AI-powered healthcare intelligence, built on its flagship Healthcare Map, which tracks more than 330 million de-identified U.S. patient journeys. Its platform supports 50+ therapeutic areas, helping life sciences companies, payers, providers, and patient advocacy groups improve outcomes, reduce costs, and accelerate access to therapies.
In July 2025, the company launched Marmot, a healthcare-native AI engine that delivers transparent, verifiable analytics in minutes and is already being used by partners such as Alnylam Pharmaceuticals. Earlier in 2025, Komodo partnered with Nasdaq to introduce the exclusive Nasdaq Medical Claims Insights dataset, providing financial institutions with visibility into payer, provider, and pharmaceutical trends.
Komodo has raised $514 million to date, including a $220 million Series E in 2021 led by Tiger Global Management at a $3.3 billion valuation, with participation from notable investors including Coatue, Dragoneer, Andreessen Horowitz, Felicis Ventures, Iconiq Capital, and others. Chief Executive Officer and Co-Founder Arif Nathoo has led Komodo since its founding in 2014, guiding its growth from a data-driven startup into one of the industry’s most influential platforms for real-world healthcare insights.
Based in Madrid, Home Medical Management (HMM) provides a digital platform that streamlines the coordination of home healthcare for payers, providers, and patients. The company delivers an interoperable system that supports scheduling, geolocation, e-prescriptions, and unified records across insurers, governments, hospitals, the social and healthcare sector, and pharmaceutical companies.
In recent years, HMM has scaled into an international player in home healthcare technology, supporting more than 600,000 scheduled visits annually and a network of over 1,500 professionals worldwide. The platform consistently delivers measurable outcomes, including cost reductions of up to 50% for payers, a 96% patient satisfaction rate, and rehospitalization rates as low as 4.6%. Clients such as OMINT’s Home Special Care program cite HMM as a proven solution for improving quality and oversight while reducing costs. Founder and Chief Executive Officer Diego Gerosa has led HMM’s growth from a regional startup into a global platform with a footprint across Europe and Latin America.
Clearwave Corporation is a patient revenue platform that helps specialty practices grow faster, collect more, and deliver a seamless patient experience. Its patient-led self-service technology is used by more than 500 practices nationwide, powering over 60 million scheduled appointments, 110 million check-ins, and $500 million in collected payments to date. With connectivity to more than 900 payers and over a billion eligibility checks completed, Clearwave enables practices to cut staff workloads by up to 87%, accelerate collections, and strengthen patient retention.
In the first half of 2025, Clearwave supported a record 22 million patients while expanding its clearwaveCARE program to provide customers with end-to-end support across onboarding, training, and long-term success. Backed by Great Hill Partners and Frontier Growth, the company is scaling its role as a major self-service platform for patient revenue optimization.
Clearwave is led by Chief Executive Officer Mike Coffey, appointed in September 2025. A four-time CEO with two decades of SaaS experience, Coffey is focused on advancing the company’s innovation roadmap while reinforcing its customer-first culture.
TriNetX is a global health technology company that operates the world’s largest federated real-world data network. It enables life sciences organizations and healthcare providers to accelerate clinical research and generate real-world evidence. The platform provides HIPAA-, GDPR-, and LGPD-compliant access to de-identified EHR and claims data, supporting millions of research queries each month across more than 25 countries.
TriNetX is used by nine of the top 15 global pharma companies, including Pfizer, Sanofi, and Novartis, and has partnered with hundreds of healthcare organizations worldwide. Founded in 2013, TriNetX has raised over $100 million in funding. Carlyle later became the company’s majority owner, helping guide its expansion into international markets.
Loftware is a global provider of product identification software, offering labeling, artwork management, and connected-packaging on a single cloud platform. The company serves more than 100,000 customers and 1,000 partners across 100+ countries, generating over 51 billion labels annually and helping brands in industries such as pharmaceuticals and medical devices.
In April 2025, Loftware expanded its capabilities with the acquisition of BL.INK, adding enterprise link management, dynamic QR codes, GS1 Digital Link, and no-code Digital Product Passports to power connected packaging and consumer engagement. The company’s growth has been supported by private-equity backers Riverside Partners since 2014 and Accel-KKR, which joined in 2023, enabling global expansion and multiple strategic acquisitions.
Chief Executive Officer Jim Bureau, who previously held leadership roles at JAGGAER and Verint, directs Loftware’s strategy to modernize product identification from new product development through manufacturing and distribution to consumer touchpoints. With certified integrations to SAP, Oracle, and Infor, Loftware positions its platform as the single system of record for labeling and packaging across complex, regulated supply chains.
ScienceSoft USA Corporation is a healthcare IT consulting and software development company with more than 750 experts and a record of over 4,000 projects since its founding in 1989. The company delivers solutions for PHI exchange, telemedicine, diagnostics, patient monitoring, and analytics, serving clients such as Rivanna Medical, ScribeAmerica, and Delaware Valley Community Health.
In July 2025, ScienceSoft launched a HIPAA-compliant AI scheduling assistant built on Amazon’s Nova Sonic model—the first to support real-time, human-like bidirectional voice conversations. Integrated with EHR, CRM, and practice management systems, the tool reduces booking times by 40% and lowers call abandonment rates by 30%, enabling providers to scale patient access while cutting costs.
Under the leadership of CEO Nick Kurayev, ScienceSoft has expanded from a product firm into a global services provider, achieving significant growth and building partnerships with Microsoft, AWS, and Oracle. Today, the company supports clinical workflows for more than 1,300 clients worldwide.
Phreesia is a provider of patient-activation solutions that help providers, payers, and life sciences organizations engage patients throughout their care journeys. Since its founding in 2005 and IPO in 2019, the company has expanded its platform from digital registration into a comprehensive suite spanning scheduling, payments, and clinical support, deeply integrated with provider workflows. In fiscal year 2025, Phreesia facilitated more than 150 million patient visits, served an average of 4,203 healthcare services clients, and generated $419.8 million in revenue, up 18% year over year.
In September 2025, Phreesia introduced VoiceAI, a 24/7 conversational AI designed to triage, route, and document common call types. That same year, the company signed a definitive agreement to acquire AccessOne for $160 million in cash, adding patient-financing capabilities expected to contribute $35 million in annualized revenue. Phreesia’s platform is used by health systems and medical groups nationwide to drive efficiency and improve patient experiences.
NextGen Healthcare offers cloud-based electronic health records, practice management, and data solutions purpose-built for ambulatory and specialty practices. The company supports more than 100,000 providers and 1 million connected caregivers across the U.S., helping to improve clinical quality, strengthen financial performance, and enhance the patient experience.
In September 2025, NextGen launched NextGen Navigator, an AI-enabled tool designed to streamline customer service and expand patient access. The company has also embedded advanced analytics throughout its platform as part of a modernization initiative driven by private equity ownership. Thoma Bravo took NextGen private in 2023 and, in May 2025, welcomed Madison Dearborn Partners as co-owner to accelerate growth and innovation.
NextGen is currently led by Chief Executive Officer David Sides, who will transition to the board following a planned leadership succession. President and Chief Operating Officer Srinivas Velamoor has been appointed to succeed him as CEO after the transition period. Velamoor, who joined the company in 2021, has directed NextGen’s technology roadmap and expansion, advancing its AI portfolio while scaling the company to more than 2,000 employees worldwide.
Epic Systems is the world’s largest provider of electronic health records, supporting more than 325 million patients globally and serving nearly every care setting. In September 2025, the company introduced Comet, a predictive intelligence system built on its Cosmos data platform and trained on more than 100 billion medical events to help clinicians anticipate risks such as readmission and disease onset. Epic reported $5.7 billion in revenue for 2024, up from $4.9 billion in 2023.
Founded in 1979 in a Wisconsin basement, Epic has grown into a global health technology leader while reinvesting roughly 35% of operating expenses into in-house R&D rather than acquisitions. Its customer base includes leading health systems such as Trinity Health, Northwell Health, UPMC, Intermountain Health, IU Health, and Baptist Health South Florida. Founder and Chief Executive Officer Judy Faulkner continues to guide the privately held, employee- and family-owned company, which she has pledged will remain independent for the long term.
H1 is a healthcare data company founded in 2018 with a mission to connect the world with the right doctors. Its platform integrates billions of data points across more than 12 million providers, 120 million publications, 800,000 clinical trials, and 17 billion claims, allowing life sciences, payers, and health systems to improve research representation, accelerate clinical development, and expand patient access. By 2025, H1 served more than 200 customers across six continents, with named partners including Medtronic, Novartis, Sanofi, Lilly, Centene, Gilead, and Memorial Sloan Kettering.
In June 2025, H1 acquired Veda to build an end-to-end provider data platform and appointed former FDA Commissioner Dr. Stephen Hahn to its board. These moves followed the acquisition of Ribbon Health, which expanded H1’s offerings for health plans and digital health. The company raised a $123 million Series C round in 2022 led by Altimeter, Goldman Sachs, IVP, Menlo Ventures, and Flex Capital, which valued the business at $773 million. Chief Executive Officer and Co-Founder Ariel Katz has led H1 since inception, steering its growth from an early-stage startup into a global leader in provider, research, and clinical data.
Kyruus Health provides a care-access platform that connects more than 500,000 providers across 1,400 hospitals, 550 medical groups, and 100 health plan brands to help people find and book care. Its platform drives digital acquisition and scheduling for health systems and plans, supporting over 1 billion annual care searches and exchanging 2.7 petabytes of data each month. Customers such as Intermountain Health have reported measurable results, including a 42% increase in bookings through the Google Reserve integration of Kyruus Reach.
The company is on track to surpass $150 million in annual recurring revenue in 2025. Growth has been fueled by major milestones, including the addition of 12 million health-plan members in 2024. In September 2025, RevSpring announced a definitive agreement to acquire Kyruus to unify search, access, intake, and payments into a single consumer experience.
Founder and Chief Executive Officer Graham Gardner, MD, directs Kyruus’s product and go-to-market strategy, including the 2025 expansion of Kyruus Reach to Google, Bing, and other AI-driven channels covering more than 90% of U.S. search traffic. The company’s portfolio also includes Kyruus Guide, an AI-assisted navigation tool, and Provider Data Solutions, which supports payer directory accuracy and network adequacy.
Relatient is a patient-access and scheduling platform used by more than 47,000 providers to serve over 50 million patients annually. Its solutions span self-scheduling, reminders, digital intake, messaging, and payments, helping health systems and medical groups reduce hold times, no-shows, and administrative backlogs while improving patient conversion across websites, chat, virtual agents, and contact centers.
In 2025, Relatient introduced Dash Direct, an open scheduling API suite that automates booking, rescheduling, cancellations, referrals, and verification across existing tech stacks, and Dash Voice AI, a conversational agent capable of handling hundreds of simultaneous appointment calls 24/7 with ~25% call deflection. Early adopters such as Raleigh Orthopaedic have reported significant staff-time savings.
Relatient originated from its 2021 merger with Radix Health, creator of Dash Schedule, and has since expanded through integrations across major practice management and EHR environments. Backed by Brighton Park Capital since 2019, the company has grown under Chief Executive Officer Jeff Gartland, who joined in 2021 and directs its transition to API-first access and AI-driven automation.
Cedar is a healthcare financial engagement platform founded in 2016 to simplify the patient billing experience and improve provider performance. Its technology unifies billing and benefits data into a single, consumer-grade payment journey used by leading health systems including Yale New Haven Health, Novant Health, Summit CityMD, and ChristianaCare. Today, Cedar engages with more than 300,000 patients each day, helping nearly three in four avoid collections while enabling providers to achieve up to a 30% lift in patient payments.
In April 2025, Cedar launched Kora, an AI voice agent built with Twilio that automates about 30% of billing calls, and partnered with Sanford Health to extend Cedar Pay to 2.4 million patients across the Midwest. The company has raised more than $350 million in funding, including a $200 million Series D in 2021 led by Tiger Global at a $3.2 billion valuation, with participation from Andreessen Horowitz, Thrive Capital, and Concord Health Partners. Chief Executive Officer and Co-Founder Florian Otto has led Cedar since inception, guiding its growth at the intersection of healthcare and financial technology.
QGenda is a healthcare workforce management company that provides cloud-based software to help organizations optimize provider deployment, staffing, and access to care. Founded in 2006 and headquartered in Atlanta, QGenda has grown into the recognized leader in healthcare workforce management under the leadership of CEO Greg Benoit, who has advanced AI-driven scheduling and mobile solutions that streamline operations across care teams.
Its ProviderCloud platform spans scheduling, credentialing, on-call management, time and attendance, clinical capacity management, and workforce analytics, supporting more than 700,000 providers across 4,500 organizations nationwide. In July 2025, QGenda expanded its capabilities with the acquisition of New Innovations, the largest residency management software provider, extending the platform to cover the full lifecycle of graduate medical education.
Cohere Health is a clinical intelligence company founded in 2020 to transform how health plans and providers collaborate on care decisions. The company’s flagship Cohere Unify platform streamlines prior authorization, with up to 90% of requests auto-approved, reducing provider friction and accelerating patient access to care. Today, Cohere processes more than 12 million prior authorization requests annually for over 600,000 providers nationwide.
In September 2025, Cohere expanded beyond utilization management with the acquisition of ZignaAI and the launch of its Payment Integrity Suite, integrating pre- and post-service data to reduce waste, improve payment accuracy, and strengthen payer-provider collaboration. In May, the company raised a $90 million Series C round led by Temasek, bringing total funding to $200 million with participation from Deerfield, Flare Capital Partners, Define Ventures, Longitude Capital, and Polaris Partners.
Chief Executive Officer and Co-Founder Siva Namasivayam, who previously built SCIO Health Analytics into a top healthcare analytics firm acquired by EXL for $240 million, has positioned Cohere as a market leader in responsible, AI-driven clinical decision support.
ELLKAY is a healthcare data connectivity and interoperability company that connects more than 58,000 organizations and integrates with over 750 EHR and practice management systems across 1,100 versions, enabling the exchange of 240 million patient records. Its platform powers clinical data migration, laboratory connectivity, and payer data solutions, helping organizations reduce costs, meet regulatory requirements, and improve patient outcomes.
In September 2025, ELLKAY was named a Technical Service Provider for CommonWell Health Alliance, supporting the expansion of nationwide data exchange. Earlier in the year, CEO Ajay Kapare represented the company at the White House during the launch of CMS’s Digital Health Ecosystem and Interoperability Framework.
Founded in 2002, ELLKAY has grown over more than two decades into a trusted partner for hospitals, health systems, laboratories, payers, ambulatory practices, and health IT vendors. Today, the company continues to scale its solutions to advance value-based care and deliver seamless, patient-centered interoperability across the healthcare industry.
Cedar Gate Technologies is a value-based care technology and services company that provides a unified platform for payers, providers, and employers to manage analytics, population health, and payment models on a single data foundation. Its solutions support arrangements such as bundled payments, primary care attribution, and global capitation, helping organizations reduce costs and improve outcomes across healthcare.
Proven at scale with more than 1,000 employees worldwide, including a large team in Nepal, the company has expanded rapidly from just 38 employees in 2018. Cedar Gate has enhanced its platform through acquisitions, including Global Healthcare Alliance in 2018 and Citra Health Solutions, Deerwalk, and Enli Health Intelligence in 2020. In 2025, GTCR, its founding private equity partner, began exploring a sale that would value Cedar Gate at more than $1 billion.
Founded in 2014 in partnership with GTCR, the company is backed by strategic investors including Ascension Ventures and Cobalt Ventures. Founder and Chief Executive Officer David B. Snow, Jr., former CEO of Medco Health Solutions, who led its $34 billion merger with Express Scripts, brings more than four decades of healthcare leadership to Cedar Gate.
Candid Health is a healthcare technology company delivering an automation-first revenue cycle platform that eliminates unnecessary manual work from medical billing. Providers across the U.S. use its infrastructure to achieve touchless claim rates above 95%, accelerate reimbursement, and reduce administrative costs, with the company now supporting more than 200 provider groups nationwide.
Chief Executive Officer and Co-Founder Doug Proctor, a veteran of Palantir Technologies, has guided Candid through rapid growth and continues to position the company as a leader in autonomous revenue cycle management. In February 2025, Candid raised a $52.5 million Series C round led by Oak HC/FT, bringing total funding to approximately $100 million and fueling expansion into multi-site provider groups and further AI-driven automation. This followed a strong 2024, when the company reported nearly 250% year-over-year revenue growth, with partners like Talkiatry reducing manual billing work by 40% while managing a 45% increase in claims volume.
Luma Health is a healthcare technology company that aims to redefine patient access through its AI-native Patient Success Platform, which is used by more than 750 healthcare organizations and 500,000 providers across the U.S. and Canada. The platform integrates with over 80 EHRs to unify scheduling, communication, and engagement, enabling more than $3.2 billion in healthcare revenue and serving health systems such as Banner Health, Montefiore Medical Center, Cook County Health, and Kelsey-Seybold Clinic.
Under its leadership team, Luma has advanced its evolution into an AI-first platform, including the October 2024 launch of Spark, a multimodal generative AI engine powering products such as Navigator, an AI voice concierge, and Fax Transform, which automates referral and intake workflows. Early adopters like the University of Arkansas for Medical Sciences and DENT Neurologic Institute have reported significant efficiency gains.
Luma Health has raised $160 million to date, including a $130 million Series C led by FTV Capital in November 2021, supporting continued expansion and product innovation. Co-Founder and Chief Executive Officer Adnan Iqbal continues to guide the company’s mission of making healthcare access seamless, helping patients get to care faster while reducing the burden on staff.
Andros is a health technology company that simplifies provider network management for health plans, government programs, and telehealth organizations. Its Arc Network Lifecycle Platform, powered by the industry’s largest provider data resource, streamlines recruitment, contracting, credentialing, and monitoring, supporting care delivery across counties covering more than 90% of the U.S. population. To date, Andros has built and managed more than 200 provider networks nationwide, helping customers improve efficiency and outcomes at scale.
Originally launched as CredSimple, the company expanded from cloud-based credentialing into full network lifecycle management, supported by investment from Questa Capital, Windham Venture Partners, and Primary Ventures. Chief Executive Officer Jeff Fritz, who joined in 2023, brings more than 20 years of leadership in health and wealth technology, including previous roles as CEO of Revel Health and founder of WEX Benefits. Under his direction, Andros continues to advance data-driven network solutions that improve operational efficiency and expand access to care.
Healthie is an API-first infrastructure platform that powers virtual-first, longitudinal healthcare delivery for more than 25,000 clinicians across specialties such as behavioral health, women’s health, nutrition, MSK, and family care. Its platform supports care for over 10 million patients, with developers making more than 1 billion API calls each month to integrate EHR, scheduling, and engagement capabilities.
In 2025, Healthie advanced its platform with the expansion of Healthie Harbor, a marketplace now supporting 57 integrated partners, and the launch of new AI-powered tools designed to streamline clinical workflows and strengthen value-based care models. These initiatives build on its ONC- and HITRUST-certified EHR and have made Healthie a backbone for digital health organizations nationwide.
Founded in 2016, Healthie most recently raised a Series B round in October 2024 to support continued growth and product innovation. Co-Founder and Chief Executive Officer Erica Jain has led the company since inception, scaling it into one of the most widely adopted infrastructure platforms in digital health.
Zus Health is a health technology company building the shared data backbone for modern care delivery. Founded in 2020, the company provides a platform that unifies patient records, spanning coverage, medications, care teams, and more, into a streamlined profile accessible at the point of care. Through its Zus Aggregated Profile, the company integrates directly into EHRs and clinical workflows, giving providers clearer patient insights and enabling faster, evidence-based decisions.
Chief Executive Officer Jonathan Bush, co-founder and former CEO of athenahealth, brings decades of health IT leadership to Zus. His vision is to make comprehensive, interoperable patient data the default infrastructure for the next generation of healthcare innovators.
Zus Health is backed by investors including Andreessen Horowitz, F-Prime Capital, Maverick Ventures, and JAZZ Venture Partners. The company partners with organizations such as Elation Health, Healthie, and Canvas Medical to power solutions for population health, value-based care, and digital-first providers.
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